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doi: 10.1111/dom.15267

That single action prolongs the sense of fullness, but it is also the direct source of the characteristic gastrointestinal side effects of the GLP-1 class, from nausea to constipation

The next generation of obesity medications pushes this further, targeting three or even four receptors simultaneously

While frequent urination is not listed as a direct side effect in FDA prescribing information, some patients report changes in urinary patterns

Conclusion In conclusion, CVOTs have played a pivotal role in evaluating the cardiovascular safety and efficacy of GLP-1 receptor agonists in patients with T2D