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Stress management: Chronic stress can lead to overeating and weight gain

MAPKs, particularly the extracellular regulated protein kinase 1/2 (ERK1/2), are associated with the leptin signaling [135, 136]

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Real-world data from weight-loss clinics show that 1525% of patients on sustained GLP-1 therapy develop deficiencies in vitamin B12, iron, or calcium within 612 months if intake and absorption are not actively managed
