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Description
Another way of action for gut-derived GLP-1 includes indirect signaling via the vagus nerve

10.1016/j.intimp.2024.111709 85 KimJ.WeiY.SowersJ

But for some people, that signal doesnt work as effectively making it harder to feel full and easier to overeat

Some patients achieve meaningful weight loss at 1.01.7 mg weekly and choose to remain at those doses due to tolerability or individual response

In a study of people with diabetes, GLP-1s increased heart rate by about 3 beats per minute
