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The theoretical concerns centre on the potential for these large peptide molecules to affect infant growth, glucose metabolism, or gastrointestinal function, though the extent of oral bioavailability following ingestion in breast milk is uncertain

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With a half-life of about six days, it takes around four to five half-lives to clear, during which its appetite-regulating and metabolic effects gradually diminish

Clinics in perinatology , 1 (2), 331-348.

is supported by a Department of Medicine, University of Toronto Merit Award, and receives support from the CIHR, Diabetes Canada and the Heart and Stroke Richard Lewar Centre of Excellence