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Looking ahead, orforglipron and retatrutide from Eli Lilly exemplify the next generation of metabolic therapies: oral formulations that promise improved adherence and triple-hormone mechanisms that deliver superior weight loss [4]

Unplanned surgery is the strongest established predictor of pulmonary aspiration, with large cohort data demonstrating a more than thirty-fold increase in risk, irrespective of the airway device choice [52]

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