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Most gastrointestinal side effects occur during dose escalation and reduce significantly over time

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[DOI] [PubMed] [Google Scholar] 257.Jakicic J.M., Marcus B.H., Lang W., Janney C

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There are two potential explanations for this case

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Discuss your reasons, concerns, and any goals you have in mind, particularly if youve used semaglutide for weight loss

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Unlike GLP-1-only treatments such as Wegovy, which primarily reduce appetite, retatrutide also directly stimulates fat metabolism through its action on glucagon receptors

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