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Description
The antiemetic actions of GIP receptor agonism

Furthermore, tirzepatide therapy in diabetic rats restored specific abnormal alterations in signal molecules related to inflammatory signaling pathways via PI3K/Akt/GSK3 signaling pathway [68]

Though Mounjaro is indicated for diabetes, only around half of new Mounjaro patients have a diabetes diagnosis, while a quarter have a weight-related diagnosis

SURPASS-AP-combo, respective clinical trial registration numbers NCT04537923, NCT04255433, NCT03861052, NCT03861039, NCT04093752) are not completed yet
Gariani K, Putzu A
