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A meta-analysis of randomized controlled trials (RCTs) including patients with HF found no improvement in hospitalization rates or echocardiographic parameters such as LVEF or LV end-systolic or diastolic volume

Ethics approval This study involves human participants and was approved by the Institutional Review Board of Charit - Universittsmedizin Berlin (Ref: EA2/041/23), Ministry of Health Jerusalem (Ref: MOH-072-2023 and Ref: ASF-0036-23), Shamir Medical Center

Similarly, converting between medications requires understanding that the appearance change has nothing to do with the effectiveness of the new medication

Immediate family was defined as a spouse, parent, child or sibling, whether biological or legally adopted

In the gastrointestinal tract, delayed gastric emptying slows nutrient delivery and contributes to early satiety, while central actions on GLP1 receptorpositive neurons in the hypothalamus and brainstem reduce hunger and alter rewardrelated eating behavior