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Description
Obesity has emerged as one of the leading global drivers of gastrointestinal and metabolic disease, contributing substantially to the burden of metabolic dysfunction-associated steatotic liver disease (MASLD), gastroesophageal reflux disease (GERD), Barrett's esophagus, pancreatitis, colorectal neoplasia, and obesity-associated malignancies
This comprehensive review explores the mechanisms, clinical implications, and mitigation strategies, including exercise, protein intake, and adjunct therapies.

Metabolic health is highly dependent on intestinal and hepatic handling of dietary and endogenous lipids and lipoproteins

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Monitoring key biomarkers, such as HbA1c levels, liver enzymes, kidney function, and lipid profiles, ensures that any underlying issues are identified and addressed promptly
