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Este fenmeno se debe a respuestas biolgicas profundamente arraigadas en nuestra fisiologa: "cuando perdemos peso, nuestros cuerpos entran en un estado de ahorro energtico, aumentando las hormonas que inducen el hambre y disminuyendo aquellas que promueven la sacieda d"

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In particular, the beneficial effects of GLP1 have been combined in dual agonists (for both GLP1 and GIP receptors or GLP1 and glucagon receptors) or triagonist (for GLP1, GIP and glucagon receptors) strategies (Capozzi et al., 2018