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Below 7.0%: Standard target for most adults with diabetes Below 6.5%: More aggressive target for some patients Below 5.7%: Normal range (non-diabetic) 87% of Retatrutide trial participants reached the 7.0% target Metformins A1C reduction typically falls in the 1.0-1.5% range when initiated as first-line therapy

These numbers were all significantly higher than those reported in the placebo group

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