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TRIUMPH-4 studied people with obesity or overweight and knee osteoarthritis
Specifically, the reduction in LFC was positively associated with the reduction in body weight, SAT, and VAT, thereby suggesting that the decrease in weight and adipose tissue is a possible mechanism for improvement in LFC

But you also hear it when people talk about proximity to failure

Because managing type 2 diabetes requires in-person medical evaluations, blood tests, and continual glucose monitoring, it cannot be managed via telehealth

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