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Proteomics, transcriptomics and histology Proteomics, bulk RNA sequencing and immunofluorescence was performed as described in Supplementary Information 1

Seizures should be controlled with benzodiazepines or, if these are ineffective, other anticonvulsants (e.g
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Tirzepatide, a dual GLP-1 and GIP receptor agonist, activates two separate appetite and metabolism pathways to produce greater weight reduction than single-agent therapies

And to ultimately address the issue, we may need more creative solutions
