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Al-Khayri JM, Sahana GR, Nagella P, Joseph BV, Alessa FM, Al-Mssallem MQ (2022) Flavonoids as potential anti-inflammatory molecules: a review
10.1016/j.bbagen.2009.11.002 106 NaW.LeeJ
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A meta-analysis of 12 randomized controlled trials (n = 17,996) further confirmed these renoprotective effects, with agents structurally closer to endogenous human GLP-1, such as semaglutide, showing the strongest benefit (RR = 0.78, 95% CI: 0.710.85) ( 3.4 Hepatic protection In clinical practice, semaglutide has demonstrated notable efficacy in resolving NASH without aggravating hepatic fibrosis
Although a role of CD4 + T cells in MASLD has been suggested [72], the exact polarization state of these cells during MASLD development remains obscure
