difference between semaglutide and glp 1 Tirzepatide vs. Semaglutide: What You Should Know Peptide Monday: Semaglutide vs Tirzepatide

Patients should be advised to: Start with the lowest dose and increase slowly Eat smaller, more frequent meals Avoid high-fat foods Stay well-hydrated Safety monitoring should include vigilance for: Pancreatitis symptoms (severe persistent abdominal pain) discontinue immediately if suspected Gallbladder disease increased risk with rapid weight loss Hypoglycaemia particularly when combined with insulin or sulphonylureas Renal function deterioration especially with dehydration from gastrointestinal effects Diabetic retinopathy monitor in patients with pre-existing retinopathy, particularly with semaglutide Suspected adverse reactions should be reported via the MHRA Yellow Card scheme

However, there is no official direct link between these medications and increased urinary frequency as a pharmacological effect of the drug class

patients should use alternative contraception for 4 weeks after initiation and each dose escalation [1] Pregnancy/lactation : Tirzepatide for weight management should be discontinued when pregnancy is recognized due to potential fetal risk

doi: 10.1186/s10020-022-00574-6 88 Moschovaki FilippidouFKirschAHThelenMKtszeriMArtingerKAringerIet al

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