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Hormonal contraceptives that are not administered orally should not be affected... I wanted to dig deeper into three concepts here: concomitantly administered, medications dependent on threshold concentrations for efficacy, and those with narrow therapeutic index

And in terms of individual drugs, it likely depends on the year

While the clinical significance remains unclear, women relying on oral contraceptives should be advised about potential interactions and may need to consider additional contraceptive methods or more frequent monitoring to ensure continued effectiveness

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