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What began as a therapeutic advance in diabetes has evolved into a broader transformation of how metabolic diseases are treated and understood

The Food and Drug Administration approved Eli Lilly's blockbuster weight loss drug Zepbound for treating patients with the most common sleep-related breathing disorder

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Contrasting the latter, loss of liver Fgf21 expression did not attenuate liraglutide-induced weight loss in mice fed a high fat (60%), low carbohydrate diet, further suggesting that the contribution of Fgf21 to weight loss by liraglutide is dependent on dietary carbohydrate content

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