glp-1 drug use before pregnancy is linked to some risks. Early Update GLP-1 Receptor Agonists in Pregnancy

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David Sinclair: GLP-1 Blindness Risk Is Real, and ALS May Be Reversible When a Harvard geneticist casually estimates that GLP-1 drugs may be causing 20,000 to 30,000 cases of sudden blindness per year in the US, then immediately pivots to say his lab's experimental therapy is being positioned to treat that very complication, you understand why longevity science has become the most watched and most confusing corner of medicine

For psyllium, this means approximately 5 grams split between morning and evening

Also, given the observational nature of the study, we could expect the presence of indication bias, a type of confounding bias that occurs when a symptom or sign of disease is judged as an indication for a given therapy, and is therefore associated both with the use of a drug and with a higher probability of an outcome related to the disease for which the agent is indicated [37]

Mounjaro may show slightly higher rates at maximum doses (nausea ~30% at 15 mg), while Rybelsus daily dosing may provide a tolerability edge through more gradual drug exposure