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GLP-1 is having a cultural momentbut it's been quietly shaping metabolic health research for decades

With its dual GIP/GLP-1 mechanism, tirzepatide is emerging as one of the most promising investigational therapies for MASH

The GLP-1RA group had greater weight loss during the weight maintenance period (2.3kg (95% CI=0.6 to 4.0)), and had fewer meal replacements per day compared with the control group (minus one meal per day (95% CI=0.6 to 1)), P<0.001
