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GLP-1 receptors are expressed in key reward-related brain regions , including: The ventral tegmental area (VTA) and nucleus accumbens , which form the core of the mesolimbic dopamine pathway The prefrontal cortex , involved in executive function and impulse control The amygdala , which processes emotional salience and stress responses The prevailing hypothesis suggests that GLP-1 receptor activation may modulate dopamine signalling in reward circuits

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In addition, it is important to note that these considerations relate to nonsurgical aesthetic treatment and should not be extrapolated to plastic surgery patients (or to those undergoing more invasive nonsurgical procedures like fat transfer)