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459 Adipose tissue-specific Nampt knockin and knockout mice (ANKI and ANKO) showed opposite alterations of circulating eNAMPT, which accordingly affected hypothalamic NAD + /SIRT1 signaling and physical activity
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Furthermore, Adequate fiber intake during GLP-1 therapy supports microbiome diversity and the production of short-chain fatty acids that nourish intestinal cells and reduce inflammation
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