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Genetic Factors That Predict Weight Regain Susceptibility Individual genetic variants influence how strongly your body responds to appetite-regulating signals and how efficiently you burn calories at rest
Crit Rev Toxicol 46(6):477489

Patients should receive guidance on protein prioritization before appetite suppression becomes pronounced, establishing eating patterns that emphasize nutrient-dense, protein-rich foods even when overall food volume decreases

Keep in mind that these are long-term treatments, and it takes time for the medication to build up in your body
