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6466 These agents improved glucose tolerance, reduced food intake, and promoted weight loss

SURMOUNT-1 results (72 weeks, adults with obesity): 5 mg dose: approximately 15% body weight loss 10 mg dose: 19.5% body weight loss 15 mg dose: 22.5% body weight loss Placebo: 3.1% body weight loss At the 15 mg maximum dose, the average participant lost about 52 pounds over 72 weeks

2 These cysts are formed in the ovarian follicles due to hormonal imbalance, specifically hyperandrogenism, which is a key manifestation of PCOS, along with ovulatory dysfunction and altered polycystic ovarian morphology

Cardiovascular protection

Med 373 , 22472257 (2015)