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[DOI] [PMC free article] [PubMed] [Google Scholar] 698.Larsen P.J., Tang-Christensen M., Jessop D.S

Using PET-CT imaging after intravenous administration of 18 F-FDG to T2DM patients treated with metformin, researchers showed that the amount of glucose entering the gastrointestinal system from the circulation was increased, which contributed to the drugs glucose-lowering effect and improved glycemic control (Koffert et al., 2017

Accordingly, informed consent and IRB review were not required for this study

Abundant evidence revealed that liver fibrosis is a key factor determining clinical outcomes in NASH patients (128)

However, sensitivity analyses, which involved excluding individual studies, revealed that omitting one outlier study [22], characterized by substantial variability compared to the others, resulted in a significant increase in WL for the GLP-1RAs group (SMD = 0.82