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The MPTP toxicity was fully reversed by exenatide, which increased the numbers of viable DAergic neurons and modulated the level of inflammation

134979-01-4, CH2COOH-PEG2-NH2.HCl References: [1] Tirzepatide demonstrated significant and superior weight loss compared to placebo in two pivotal studies, [2] Lilly's tirzepatide achieved up to 15.7% weight loss in adults with obesity or overweight and type 2 diabetes in SURMOUNT-2

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While the authors note that further clinical validation is needed, they encourage dermatologists to consider GLP-1RA therapy to improve psoriatic disease care in people with psoriasis and obesity while potentially realizing additional benefits