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These studies consistently demonstrated that the medication maintained its weight-lowering effect without unexpected safety signals emerging during the extended treatment window

Within the GLP-1RA group, discontinuing treatment for even 0.5 years was associated with a higher MACE risk compared to continued use

HEK293T cells in 6-well plates were transfected with 0.2 g SNAP-GLP-1R-NLuc, 0.2 g Nb37-GFP (a gift from Dr Roshanak Irranejad, UCSF), plus 1.6 g pcDNA3.1, for 24 hours before the assay

The BSH gene, a gene encoding the production of BSH by the intestinal microbiota, is associated with obesity and T2DM was significantly correlated (Jia et al., 2020)

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