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As a result, you feel full for a more extended period after eating, reducing the urge to consume additional calories

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Hunger increases, fullness becomes less reliable, and metabolic adaptation makes maintenance difficult

No differences in DPP-4 Another novel finding researchers discovered involved the enzyme dipeptidyl peptidase-4 (DPP-4), which breaks down GLP-1 and GIP after they are secreted

Appetite is lower, thirst may be blunted, and some patients develop nausea, constipation, or both