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Improvements in blood pressure within the 48-week treatment period resulted in the discontinuation of at least one antihypertensive medication in 41% of the participants in the combined 8 mg group and 30% of the participants in the 12 mg group

Furthermore, a VMH knockout mouse showed lower energy expenditure and UCP1 expression in BAT62,63)

[1] Unsupervised microdosing without appropriate medical oversight could lead to inadequate treatment