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After reviewing several large epidemiological studies, clinical trial and in-market data, EMAs Pharmacovigilance Risk Assessment Committee has concluded non-anterior ischemic optic neuropathy is a very rare side effect of Ozempic, that may affect up to one in 10,000 people taking semaglutide.

A review of the medical records of thousands of adolescents treated for obesity found that kids who received the GLP-1 medications semaglutide or liraglutide were less likely to have suicidal thoughts or attempts than those treated with behavioral interventions.