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Efficacy, safety, and tolerability of exenatide once weekly in patients with type 2 diabetes mellitus: An integrated analysis of the DURATION trials

These longitudinal data will also reveal whether continuous therapy is required and how to taper or re-initiate treatment in growing children

Study Used AI to Analyze Real-World Patient Reports To better understand how people experience GLP-1 drugs outside of clinical trials, researchers used AI to analyze Reddit posts from 2019 to 2025

We are only beginning to understand how deep it goes

When to seek medical attention: Persistent vomiting preventing adequate fluid intake Severe abdominal pain, particularly if localized to the upper right quadrant (potential gallbladder issues) Severe pain in the upper abdomen radiating to the back (possible pancreatitis) Signs of dehydration (dark urine, dizziness, decreased urination) Inability to tolerate any food or liquids for more than 24 hours Severe constipation with abdominal distension or vomiting (possible ileus/obstruction) Yellowing of skin/eyes with fever and abdominal pain Patients with significant vomiting or diarrhea should be monitored for signs of acute kidney injury, particularly those with pre-existing renal impairment or taking medications that affect kidney function