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The Role of Estrogens in Control of Energy Balance and Glucose Homeostasis

The current evidence suggests that: Dose-dependent efficacy : Both glycaemic and weight outcomes improve with increasing doses within the therapeutic range, suggesting that very low doses are unlikely to provide substantial benefit

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Scenario: Stall After Months on 12mg If you have been on the maximum 12mg dose for several months and recently stalled, dose increase is not an option