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IBS is a common functional gut disorder, affecting an estimated 1015% of adults (especially women), and is characterized by chronic abdominal pain and changes in bowel habits

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Clinical trials indicate 15-25% average body weight reduction over 6-12 months, depending on the medication (e.g., more with tirzepatide) and factors like starting weight, lifestyle, and eating habits

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Clinical study demonstrating that acute GLP-1 infusion reduces glomerular hyperfiltration and produces an increase in urinary sodium excretion and a decrease in urinary hydrogen excretion in insulin-resistant obese men