blindness from glp-1 NAION and GLP1s: Rare Cause of Linked to Medication | Michael Weintraub, MD posted on the topic Researchers Find Small Increased Risk
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was funded by an MRC Clinical Research Training Fellowship

The ratio of benefit to side effects may be similar

When we are in our menopausal years, when we are at a very high risk of cardiovascular events, we know that's the leading cause of death of women when they pass menopause When anyone [00:10:00] talks about GLP ones, everyone just thinks like ozempic, sometimes wegovy, those are semaglutide and those are given as a weekly injection
Additionally, GLP-1 medications have been shown to have beneficial effects on cardiovascular health, further contributing to their appeal in treating type 2 diabetes and beyond
26 27 Additionally, GLP-1-mediated modulation of pain pathways, particularly via microglial activation in the caudal trigeminal nucleus, may exacerbate central sensitization and worsen headache symptoms