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Knudsen and her colleagues also recognized and began studying the powerful weight loss effects of liguratide, and they discovered that it binds to neurons in the arcuate nucleus, a region of the brain involved in regulating food intake and energy expenditure (4)

Long-term cardiovascular effects Heart disease and heart failure are more common in people with overweight or obesity, and treatment options have often been limited

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In 2020, only around 3%-5% of GLP-1 prescriptions required prior authorization

What to Discuss With Your GP Before Taking Both Before commencing treatment with both Ozempic and Topamax, a comprehensive discussion with your GP or specialist is essential