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N Engl J Med 2016;375:183444

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Your provider may recommend temporarily pausing dose escalation, adjusting your maintenance dose, or exploring alternative GLP-1 formulations better suited to your gastrointestinal tolerance

Melatonin regulates intestinal immune function and down-regulates inflammatory response In prolonged paradoxical sleep deprivation mouse model, with the activation of the HPA, a large amount of cortisol were released into the systemic circulation, which would mediate the disturbance of intestinal microbiota (Gao et al., 2021)

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