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Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target

This competitive pressure, combined with government negotiation and eventual generic entry, creates a trajectory toward more affordable GLP-1 access over the next five to ten years

Wegovy is FDA-approved for chronic weight management in adults with obesity
ArticlePubMed 18
10:114-132 [PMC free article: PMC6379733] [PubMed: 30788048] 204