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Across the RCTs, CoQ10 dropped: Systolic BP by 16.6 mm Hg Diastolic BP by 8.2 mm Hg (both with no change in the placebo group) In the crossover study, CoQ10 dropped: Systolic BP by 11 mm Hg Diastolic BP by 8 mm Hg Even in open-label studies (less controlled), CoQ10 dropped: Systolic BP by 13.5 mm Hg Diastolic BP by 10.3 mm Hg These numbers are on par with most commonly prescribed antihypertensive (blood pressure) drugs

10.1007/s40265-023-01932-2 66

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With that diagnosis, people with T1D are also lacking many other hormones related to fullness, insulin sensitivity and weight control, including: amylin, glucagon, pancreatic polypeptide, somatostatin and ghrelin