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Description
Once the substrate is appropriately positioned, the activated serine nucleophile of the catalytic triad (Ser630) can attack the peptide bond between the second and third residue, and form a tetrahedral covalent intermediate
Cohorts receiving VK2735 also demonstrated reductions in mean body weight relative to placebo
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Talking with your doctor can help you better assess your risk profile and whether this treatment can help you meet your weight goals
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