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16 However, the onset of obesity results in lipid accumulation within muscles, impairing glucose regulation mechanisms

These sensations are achieved as GLP-1 receptors are present in the areas of the brain that regulate appetite and food intake

In diabetes, the body is unable to make sufficient insulin (Type 1 diabetes) or insulin becomes less effective at its job (Type 2 diabetes)

This is because HbA1c reflects average blood glucose over the preceding two to three months, so changes accumulate gradually as red blood cells turn over