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"Especially when these drugs become generic, it is a real possibility that we will expand their use into patients at high risk, both for cardiovascular disease and for the development of diabetes," he said

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People who continued the treatment lost about 16.6% of their body weight as compared to a 2.7% increase with placebo

Common reasons for discontinuation were identified as high drug costs, side effects, and supply shortages, though the article notes that prices have reportedly started to decrease since the study's 2021-2023 observation period

Acknowledgements The authors of this article are supported by grants from the American Heart Association (0930366N to R.C.), the American Diabetes Association (7-09-BS-17 and 7-12-BS-010 to C.B.), the Richard and Susan Smith Family Foundation Pinnacle Program Project (7-05-PPG-02 to C.B.), the Boston Obesity Nutrition Research Center (DK46200 to C.B.) and by grants from the US National Institutes of Health (DK080836 to R.C