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The researchers pointed out that many patients in the observation group began taking nivolumab once it was approved or withdrew from the study, which may have skewed the results and made the overall survival data difficult to interpret

Retatrutide remains under clinical investigation and has not yet received regulatory approval, with ongoing Phase 3 trials evaluating long-term safety and effectiveness

Further reading: How to take GLP-1 tablets Injections are usually taken once weekly using a pre-filled pen

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Furthermore, as weight decreased, PHQ-9 and GAD-7 scores significantly declined, while SF-36 scores significantly increased