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Prospective, longitudinal studies are needed to further elucidate these effects and optimize perioperative strategies in orthopedic populations

Research demonstrates that GLP-1 therapy alone may reduce bone density without concurrent exercise (JAMA Network)

[DOI] [PMC free article] [PubMed] [Google Scholar] 121.Sodhi M, Rezaeianzadeh R, Kezouh A, Etminan M
Buse JB, Wexler DJ, Tsapas A et al (2020) 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018

Many have also had clinical trials
