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Alongside the anticipated CV safety of many of these agents, evidence for certain sodiumglucose transporter 2 (SGLT2) inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have revealed potential cardioprotective effects in patients with T2D who are at high risk of CVD events

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Onikepe Adegbola, MD PhD If you're weighing semaglutide versus tirzepatide whether for weight loss or type 2 diabetes you're asking one of the most common questions I hear in clinical practice

Most patients on semaglutide lose 13 pounds in the first month, though some see little change initially