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An additional recent study found that GLP-1 action on human pancreatic islet alpha-cells was mediated independently of any paracrine signalling, as preventing insulin and somatostatin signalling did not affect the inhibition of glucagon secretion

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This information supports provider conversations about personalized expectations and monitoring, though it doesn't guarantee specific outcomes

Endocrinology 139:37803786 Cordier-Bussat M, Bernard C, Levenez F et al

the blend requires per-component verification (two HPLC runs, two MS identity confirmations)
