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Larger and longer trials are needed to understand durability, uncommon adverse events, discontinuation rates, and how results apply to people with complex medical histories

Kidney Issues: Semaglutide can affect kidney function, especially in people with pre-existing kidney conditions

In addition, our medical and device therapies for HFpEF have expanded over the years and now include several treatments with clinical benefits and more are in development

The STEP 8 clinical trial compared the effect of weekly subcutaneous semaglutide vs liraglutide (daily) in obese and overweight patients without type 2 diabetes
