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A decrease in LAV was observed in the HFrEF population (WMD: -5.4 ml [95% CI: -8.8, -2.0]
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Looking ahead, the influence of US policy and Most Favoured Nation (international reference) pricing will remain a central trend that shaped obesity care in 2025 and will continue to do so into 2026 and beyond
Clinical Frameworks: Defining Obesity Beyond Body Mass Index (BMI) An important milestone of 2025 was the publication of The Lancet Diabetes & Endocrinology Commission on the Definition and Diagnostic Criteria of Clinical Obesity
