semaglutide give you diarrhea Side Effects: What Need to Know How to Manage (or Prevent)

Molecular Psychiatry .

Now there are three main GLP-1 treatments that are legally available in the UK - Wegovy pill (oral semaglutide): This is the latest (MHRA-approved 11 June 2026) and the first oral GLP-1 weight loss tablet licensed in the UK

In the STEP-HFpEF trial, treatment with 2.4 mg of the glucagon-like peptide-1 receptor agonist semaglutide weekly produced substantial improvements in symptoms, physical limitations and exercise function and reduced inflammation and resulted in greater weight loss compared to placebo 11,12

Week 16 and Beyond: Reaching Maintenance By week 16, you may have lost 15-20 pounds or more, depending on your starting weight

The goal isnt simply to lose pounds