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Garvey WT , 2023, Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2), Lancet 402 10402 7

The biotech firm Metsera, which is developing a once-monthly GLP-1 injection, became the object of a bidding war between Pfizer and Novo Nordisk, with Pfizer emerging as the winner

EMT Reversal in Human Cancer Cells after IR Knockdown in Hyperinsulinemic Mice
Glucose, metformin, and AICAR regulate the expression of G protein-coupled receptor members in INS-1 beta cell

Although well-established metabolic effects are observed in diabetes and obesity, the impact on body weight and dysfunctional adiposity is less marked in normoglycemic PD patients
