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While the evidence is thin, one study in the paper above did show nearly half of patients on methadone experienced excessive sweating

The Noom program has comprehensive data on patient health, injection dates, side effects, and weight-loss speed, and we bring that data to bear to personalize the dosing to maximize outcomes and adherence not just to the medication, but to our Noom microhabits program. Fear of side effects has kept many eligible users from trying GLP-1 medications, but for others, the bigger barrier is cost

The incidence rate of each gastrointestinal AE per 1000 person-years at risk was calculated, using the previously described censoring approach

23 Given the speed of divergence of the curves, it is unlikely that the pleiotropic effects of GLP-1 RAs, including reduction of SBP (by 2 to 3 mm Hg) and low-density lipoprotein cholesterol (by 0.1 to 0.2 mmol/L), along with significant weight loss, 28 would be responsible for the benefit

After randomization, few participants in either arm experienced dose adjustments or temporary or permanent discontinuations of treatment because of GI AEs (Table S2)