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Non-GLP-1 weight loss medications offer alternatives for patients who cannot tolerate GLP-1 agents or require different mechanisms of action

Genetically-predicted GLP1R expression (the target of GLP-1 RAs) showed an inverse association with background [odds ratio (OR)=0.83, 95% CI, 0.710.97] and severe nonproliferative DR (OR=0.72, 95% CI, 0.530.98), and a non-significant association with overall (OR=0.97, 95% CI, 0.921.03) and proliferative DR (OR=0.98, 95% CI, 0.911.05)

Gallbladder removal changes how your body processes bile and fat, which can affect weight loss medication choices

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